Table 3.
Body weights (gram, mean ± SD) | ||||
---|---|---|---|---|
Dose (mg/kg) | % Micronucleated PCEs (meanb ± SD) | Ratio PCE:NCE (mean ± SD) | Administration | Sacrifice |
0 (Vehicle controla) | 0.16 ± 0.06 | 0.45 ± 0.04 | 33.74 ± 0.89 | 33.87 ± 0.96 |
500 | 0.15 ± 0.13 | 0.45 ± 0.09 | 33.53 ± 1.29 | 33.82 ± 1.26 |
1000 | 0.25 ± 0.07 | 0.50 ± 0.04 | 33.32 ± 1.27 | 33.58 ± 1.08 |
2000 | 0.20 ± 0.03 | 0.49 ± 0.04 | 33.58 ± 1.17 | 33.79 ± 1.12 |
2.0 (positive controlc) | 10.87 ± 1.08* | 0.38 ± 0.03* | 33.15 ± 1.13 | 33.51 ± 1.19 |
Corn oil.
Mean of 2000 micronucleated PCEs per mouse.
Mitomycin C.
Statistically different from vehicle control group, p<0.01.