Table 6.

Summary of food consumption data in rats’ subchronic 13-week oral toxicity study.

Weeks	Control (G1)	250 mg/kg/day (G2)	500 mg/kg/day (G3)	1000 mg/kg/day (G4)
Males
0	24.25 ± 1.83	25.00 ± 1.82	20.75 ± 7.80	25.26 ± 1.85
1	27.90 ± 2.00	23.12 ± 6.65	26.24 ± 2.49	28.36 ± 1.26
2	29.92 ± 2.57	27.67 ± 1.56	28.41 ± 2.72	30.51 ± 3.15
3	31.48 ± 4.40	27.95 ± 2.42	29.33 ± 4.07	32.17 ± 3.43
4	33.44 ± 5.80	28.22 ± 2.68	30.92 ± 5.00	35.17 ± 8.09
5	31.88 ± 4.78	27.58 ± 2.58	28.69 ± 3.63	30.35 ± 2.56
6	30.43 ± 2.73	27.67 ± 1.52	27.42 ± 2.73	29.79 ± 2.04
7	29.33 ± 8.61	28.82 ± 1.17	29.12 ± 2.57	31.21 ± 2.39
8	32.32 ± 4.34	26.93 ± 2.11a	28.14 ± 2.53a	31.10 ± 2.16
9	28.29 ± 6.29	28.42 ± 3.29	27.74 ± 3.51	30.30 ± 2.92
10	28.42 ± 2.88	24.86 ± 5.63	27.11 ± 2.25	30.28 ± 1.19
11	28.88 ± 2.66	25.72 ± 1.69	26.48 ± 2.17	28.52 ± 1.83
12	28.36 ± 3.56	26.07 ± 2.23	25.00 ± 3.14	29.32 ± 2.16
13	25.31 ± 4.19	26.27 ± 2.21	25.20 ± 1.90	28.03 ± 1.31
Fold gain	1.04	1.05	1.21	1.11

Weeks	Control	250 mg/kg/day	500 mg/kg/day	1000 mg/kg/day
Females
0	18.09 ± 2.02	20.19 ± 1.50	18.40 ± 1.73	18.76 ± 2.15
1	19.46 ± 3.24	18.17 ± 3.30	19.63 ± 2.06	17.44 ± 2.47
2	21.78 ± 3.01	20.06 ± 3.32	16.74 ± 3.32	17.53 ± 3.55
3	21.00 ± 1.20	19.61 ± 4.00	22.12 ± 2.68	19.86 ± 3.41
4	22.93 ± 3.55	20.35 ± 2.99	23.23 ± 2.24	18.84 ± 1.92
5	23.80 ± 2.24	20.96 ± 3.74	22.62 ± 2.16	21.76 ± 2.73
6	23.22 ± 2.00	21.16 ± 1.15	20.27 ± 4.37	19.91 ± 3.07
7	20.03 ± 2.86	17.78 ± 1.90	20.17 ± 1.84	18.13 ± 2.65
8	21.19 ± 4.37	17.25 ± 3.08	18.65 ± 3.17	17.69 ± 1.48
9	22.06 ± 2.39	18.03 ± 2.52	19.66 ± 2.11	19.23 ± 3.34
10	17.72 ± 2.00	16.21 ± 0.96	15.90 ± 3.46	17.47 ± 1.54
11	17.63 ± 1.31	16.87 ± 3.14	17.73 ± 3.71	16.79 ± 1.61
12	20.32 ± 3.19	17.66 ± 2.98	19.14 ± 1.59	15.01 ± 1.65a
13	18.03 ± 2.05	18.05 ±4.23	16.34 ± 2.26	16.75 ± 2.72
Fold gain	1.00	0.89	0.89	0.89

Values are Mean ± SD.

^aSignificant difference compare with control group value, p < 0.05.