Table 1.
Demographic and clinical characteristics of the patients enrolled in this study.
| Characteristics | Survivor (n=46) | Nonsurvivor (n=26) | P |
|---|---|---|---|
| Age, month, median (IQR) | 12 (7, 33) | 18 (10, 84) | 0.213 |
| Male, n (%) | 30 (65.2) | 13 (50) | 0.206 |
| Source of sepsis | |||
| Lungs, n (%) | 25 (54.3) | 11 (42.3) | 0.326 |
| Abdominal, n (%) | 13 (28.3) | 11 (42.3) | 0.225 |
| CNS, n (%) | 4 (8.7) | 1 (3.8) | 0.437 |
| Haematogenous, n (%) | 2 (4.3) | 2 (7.7) | 0.552 |
| Skin/soft tissues, n (%) | 2 (4.3) | 1 (3.8) | 0.919 |
| Pediatric risk of mortality III (PRISM III), median (IQR) | 10 (5, 13) | 12.5 (9, 19) | 0.058 |
| Complications | |||
| Hemophagocytic syndrome, n (%) | 7 (15.2) | 5 (19.2) | 0.661 |
| Hematologic malignancy, n (%) | 4 (8.7) | 4 (15.4) | 0.386 |
| Adjuvant treatment | |||
| CRRT, n (%) | 13 (28.3) | 6 (23.1) | 0.632 |
| Mechanical ventilation, n (%) | 17 (40.0) | 18 (69.2) | 0.008 |
| Transferred from the other ward, n (%) | 14 (30.4) | 6 (23.1) | 0.503 |
| MAP∗ (mmHg) | 67 (61–73) | 66 (57–76) | 0.518 |
| PaO2/FiO2∗ (mmHg) | 331 (241–410) | 300 (203–365) | 0.078 |
| sCr∗ (μmol/L) | 26.5 (20.0–43.0) | 31.5 (22.0–48.0) | 0.443 |
| BUN∗ (mmol/L) | 4.2 (2.9–7.1) | 5.5 (3.2–11.0) | 0.212 |
| Lac∗ (mg/dL) | 2.3 (1.3–3.6) | 2.7 (1.4–5.2) | 0.303 |
| PLT∗(∗109/L) | 183 (119–333) | 157 (57–208) | 0.199 |
| Major pathogen | |||
| Gram-negative bacterium | 22 | 13 | 0.859 |
| Acinetobacter baumannii | 7 | 5 | |
| Pseudomonas aeruginosa | 5 | 2 | |
| Klebsiella pneumoniae | 3 | 3 | |
| Haemophilus influenzae | 4 | 0 | |
| Enterobacter cloacae | 0 | 2 | |
| Others | 3 | 1 | |
| Virus | 14 | 4 | 0.157 |
| EBV | 11 | 3 | |
| CMV | 3 | 1 | |
| Gram-positive bacterium | 8 | 4 | 0.826 |
| Streptococcus pneumoniae | 1 | 2 | |
| Staphylococcus aureus | 2 | 1 | |
| Enterococcus gallinarum | 2 | 0 | |
| Enterococcus faecium | 1 | 1 | |
| Staphylococcus capitis | 1 | 0 | |
| Others | 1 | 0 | |
| Mycoplasma | 2 | 1 | 0.919 |
CNS: central nervous system; CRRT: continuous renal replacement therapy; MAP: mean arterial pressure; PaO2/FiO2: the ratio of the partial pressure of oxygen in arterial blood (PaO2) to the inspired oxygen fraction (FiO2); sCr: serum creatinine; BUN: blood urea nitrogen; Lac: lactate; PLT: platelet. ∗Indicated that data were treated with Ln processing.