Table 3.
Associations between SP-ECog and participant Cogstate scores
| Cogstate subtest | Estimate | Standard Error | P value | Residual error | Effect size | R2 | Other significant variables | Significant interactions with SP-ECog |
|---|---|---|---|---|---|---|---|---|
| Whole cohort, n = 2693 | ||||||||
| DET (time) | 0.04 | 0.01 | .003 | 0.09 | 0.44 | 0.292 | Spouse, YK | |
| IDN (time) | 0.01 | 0.01 | .562 | 0.07 | 0.08 | 0.255 | Spouse, YK | |
| ONB (accuracy) | −0.04 | 0.04 | .235 | 0.25 | 0.17 | 0.245 | Spouse, YK | |
| OCL (accuracy) | −0.05 | 0.02 | .010 | 0.14 | 0.37 | 0.249 | Edu | Spouse |
| CU only, n = 2354 | ||||||||
| DET (time) | 0.00 | 0.01 | .900 | 0.09 | −0.02 | 0.047 | Gender∗ | YK |
| IDN (time) | 0.00 | 0.01 | .690 | 0.06 | 0.06 | 0.042 | ||
| ONB (accuracy) | −0.04 | 0.03 | .207 | 0.20 | 0.20 | 0.034 | ||
| OCL (accuracy) | −0.04 | 0.02 | .092 | 0.15 | 0.27 | 0.065 | Edu | Spouse |
| MCI only, n = 250 | ||||||||
| DET (time) | 0.23 | 0.03 | <.001 | 0.09 | 2.46 | 0.340 | Gender,† Edu | Spouse, YK |
| IDN (time) | 0.05 | 0.03 | .01 | 0.08 | 0.70 | 0.254 | Gender,† Edu | Spouse, YK |
| ONB (accuracy) | 0.12 | 0.09 | .186 | 0.28 | 0.44 | 0.340 | Gender,∗ Edu | Spouse |
| OCL (accuracy) | −0.02 | 0.05 | .658 | 0.14 | 0.15 | 0.259 | Gender,∗ Edu | |
| AD only, n = 65 | ||||||||
| DET (time) | 0.11 | 0.02 | <.001 | 0.07 | 1.62 | 0.519 | Age, gender,∗ Edu, GDS | YK |
| IDN (time) | 0.13 | 0.01 | <.001 | 0.05 | 2.48 | 0.442 | Age, gender,∗ Edu | |
| ONB (accuracy) | −0.22 | 0.06 | <.001 | 0.22 | 1.00 | 0.194 | ||
| OCL (accuracy) | −0.09 | 0.02 | <.001 | 0.08 | 1.14 | 0.397 | Gender,∗ Edu | Spouse, YK |
| CU with subjective memory concern, n = 1582 | ||||||||
| DET (time) | 0.01 | 0.02 | .538 | 0.08 | 0.14 | 0.098 | ||
| IDN (time) | 0.01 | 0.01 | .218 | 0.05 | 0.28 | 0.139 | Gender∗ | Spouse |
| ONB (accuracy) | −0.11 | 0.05 | .020 | 0.20 | 0.53 | 0.076 | ||
| OCL (accuracy) | −0.08 | 0.03 | .005 | 0.13 | 0.64 | 0.224 | Edu | YK |
Abbreviations: AD, Alzheimer's disease; CU, cognitively unimpaired; DET, detection task to measure processing speed; Edu, education level; GDS, Geriatric Depression Scale; IDN, identification task to measure attention; MCI, mild cognitive impairment; OCL, One Card Learning; ONB, One-Back Test; SP-ECog, Study partner-reported Everyday Cognition scale score; Spouse, spouse partners; YK, number of years that the dyad has known each other.
NOTE. The “Other significant variables” column includes all variables with P < .05 and effect size >0.2 in the multivariable models. Significant dyad relationship variables includes those dyad relationship variables with a significant interaction with SP-ECog, P < .05, and effect size >0.20.
Bold values indicate statistical significance of P < .001.
Females score worse than males.
Males score worse than females.