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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Stroke. 2018 Sep;49(9):2200–2210. doi: 10.1161/STROKEAHA.118.021179

Figure 6.

Figure 6

DPI treatment decreased ROS formation, cytosolic labile zinc accumulation, and ischemic brain injury only at 24h after reperfusion. DPI was injected intraperitoneally 30min before MCAO. (A) Effect of DPI on ROS formation as indicated by H2DCF-DA-stained cells. (B) Effect of DPI on zinc accumulation as indicated by NG-stained cells. Bars=20μm. (C) Effect of DPI on cerebral infarction volume, assessed by TTC-stained coronal sections. (D) Effect of DPI on neurological assessment and motor function, assessed by neurological deficit scores and foot-fault-placing test. Data are means±SD (n=5 for A&B; n=8 for C&D). *P<0.05 vs vehicle-treated MCAO group.