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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: Ann Epidemiol. 2018 May 17;28(8):549–556. doi: 10.1016/j.annepidem.2018.05.002

Table 3a.

Results from Linear Mixed Effects Models for Log-Transformed eGFR with Random Intercepts and Slopes among Children with a Glomerular CKD Diagnosis.

Model
Parameter Null Proteinuria only FGF23 only Proteinuria and FGF23
Fixed effect level
 Constant (Proteinuria= 0.45, FGF23= 110) 4.113 ± 0.029 4.117 ± 0.027 4.14 ± 0.025 4.138 ± 0.024
 log2(Proteinuria/0.45) 0 −0.074 ± 0.014 0 −0.039 ± 0.013
 log2(FGF23 / 110) 0 0 −0.219 ± 0.026 −0.187 ± 0.027
Fixed effect slope (years from baseline)
 Constant (Proteinuria= 0.45, FGF23= 110) −0.087 ± 0.010 −0.082 ± 0.009 −0.082 ± 0.010 −0.080 ± 0.009
 log2(Proteinuria/0.45) 0 −0.033 ± 0.005 0 −0.029 ± 0.005
 log2(FGF23 / 110) 0 0 −0.044 ± 0.011 −0.022 ± 0.010
Random effects
 S.D. (level) [σ1] 0.379 0.349 0.316 0.308
 S.D. (slope) [σ2] 0.111 0.084 0.103 0.082
 Correlation [σ12σ1σ2] 0.377 0.262 0.221 0.173
 S.D. residual [σ] 0.139 0.141 0.139 0.141
AIC 91.109 39.553 32.108 5.383

Bold indicates p<0.05 for fixed effects. Estimates ± Standard errors. Corresponding 95% confidence intervals may be calculated as ± 1.96 × Standard errors.

Abbreviations: S.D., standard deviation; SBP z-score, systolic blood pressure z-scores based on the normal population adjusted for age, gender and height; FGF23, fibroblast growth factor 23; AIC, Akaike’s information criterion