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. Author manuscript; available in PMC: 2019 Apr 2.
Published in final edited form as: Methods Enzymol. 2018 Apr 2;604:405–424. doi: 10.1016/bs.mie.2018.02.016

Fig. 4.

Fig. 4

NapH1 chlorination and cyclization of naphthomevalin (or methylated analogue SF2451B1) to tricyclic napyradiomycin A1 (or SF2451B3). (:B represents a general base in the reaction).