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Electrical stimulus dose–response. (A) The magnitude of the diffusion fMRI response, Δλ⊥, increases in proportion to the number of electrical impulses carried by the nerve fibers during periods of sustained electrical activity (error bars represent SEM). (B) For Δλ||, the trend is similar; however, presumably due to increased scatter in the lower spatial resolution imaging data, the correlation between impulse count and Δλ|| diffusion fMRI response is not as robust.
