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. 2018 Oct 9;115(43):11024–11029. doi: 10.1073/pnas.1807258115

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Fig. 2. — IF analysis of DNA–RNA hybrids and dsRNA in mitochondria of mtEXO-depleted HeLa cells. (A) Representative IF of S9.6 (hybrids) and J2 (dsRNA) granules in siSUV3 HeLa cells in control conditions [buffer only, untreated (utr)] or treated in vitro with RNase H (RH), RNase III (R3), or both. Nuclei were stained with DAPI. (B) Quantification of S9.6 granules per cell and (C) intensity. (D) Quantification of J2 granules per cell and (E) intensity. ****P < 0.0001 according to Mann–Whitney U test.