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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: J Mol Cell Cardiol. 2018 Apr 5;118:183–192. doi: 10.1016/j.yjmcc.2018.04.002

Fig. 2. Deletion of AR exacerbates early contractile dysfunction in mice subjected to transverse aortic constriction.

Fig. 2

WT and AR-null mice were subjected to TAC or sham surgery and long axis m-mode echocardiographic data were acquired at the indicated times after TAC. (A) Ejection fraction and (B) cardiac output (CO), at 1, 2, 4, 8 and 16 weeks after TAC. (C) Ratio of left ventricle (LV) to tibia length (TL), (D) fold change in ANF and β-MHC mRNA expression in LV of TAC hearts compared with WT sham after 2 weeks of surgery. Data are mean ± SEM, n=12–15 mice per group. *p<0.05 vs WT sham and #p<0.05 vs WT TAC.