Table 1.
The correlation between preoperative CAR and clinicopathological characteristics
| Variable | Cases (n=131) | CAR ≤0.2 (n=83) | CAR >0.2 (n=48) | P-value |
|---|---|---|---|---|
|
| ||||
| Age | 0.001 | |||
| ≤65 years | 65 (49.6) | 50 (60.2) | 15 (31.3) | |
| >65 years | 66 (50.4) | 33 (39.8) | 33 (68.8) | |
| BMI | 0.033 | |||
| <24 | 77 (58.8) | 43 (51.8) | 34 (70.8) | |
| ≥24 | 54 (41.2) | 40 (48.2) | 14 (29.2) | |
| Gender | 0.754 | |||
| Male | 113 (86.3) | 71 (85.5) | 42 (87.5) | |
| Female | 18 (13.7) | 12 (14.5) | 6 (12.5) | |
| Smoking history | 0.055 | |||
| No | 69 (52.7) | 49 (59.0) | 20 (41.7) | |
| Yes | 62 (47.3) | 34 (31.0) | 28 (58.3) | |
| Hypertension | 0.071 | |||
| No | 99 (75.6) | 67 (80.7) | 32 (66.7) | |
| Yes | 32 (24.4) | 16 (19.3) | 16 (33.3) | |
| Diabetes mellitus | 0.22 | |||
| No | 108 (82.4) | 71 (85.5) | 37 (77.1) | |
| Yes | 23 (17.6) | 12 (14.5) | 11 (22.9) | |
| Cardiovascular disease | 0.157 | |||
| No | 76 (58.0) | 52 (62.7) | 24 (50.0) | |
| Yes | 55 (42.0) | 31 (37.3) | 24 (50.0) | |
| Histology type | 0.88 | |||
| Transitional cell carcinoma | 110 (84.0) | 70 (84.3) | 40 (83.3) | |
| Non-transitional cell carcinoma | 21 (16.0) | 13 (15.7) | 8 (16.7) | |
| Grade | 0.507 | |||
| 1 and 2 | 17 (13.0) | 12 (14.5) | 5 (10.4) | |
| 3 | 114 (87.0) | 71 (85.5) | 43 (89.6) | |
| T-stage | 0.001 | |||
| NMIBC | 54 (41.2) | 43 (51.8) | 11 (22.9) | |
| MIBC | 77 (58.8) | 40 (48.2) | 37 (77.1) | |
| N-stage | 0.01 | |||
| Negative | 116 (88.5) | 78 (94.0) | 38 (79.2) | |
| Positive | 15 (11.5) | 5 (6.0) | 10 (20.8) | |
| M-stage | 0.259 | |||
| Negative | 125 (95.4) | 81 (97.6) | 44 (91.7) | |
| Positive | 6 (4.6) | 2 (2.4) | 4 (8.3) | |
| ASA grade | 0.092 | |||
| 1 and 2 | 117 (89.3) | 77 (92.8) | 40 (83.3) | |
| 3 and 4 | 14 (10.7) | 6 (7.2) | 8 (16.7) | |
| NLR | <0.001 | |||
| ≤3.8 | 90 (68.7) | 69 (83.1) | 21 (43.8) | |
| >3.8 | 41 (31.3) | 14 (16.9) | 27 (56.3) | |
| PLR | 0.002 | |||
| ≤210.9 | 112 (85.5) | 77 (92.8) | 35 (72.9) | |
| >210.9 | 19 (14.5) | 6 (7.2) | 13 (27.1) | |
| PNI | <0.001 | |||
| ≤38.5 | 114 (87.0) | 80 (96.4) | 34 (70.8) | |
| >38.5 | 17 (13.0) | 3 (3.6) | 14 (29.2) | |
Note: P-values <0.05 are shown in bold.
Abbreviations: ASA, American Society of Anesthesiologists; BMI, body mass index; CAR, C-reactive protein/albumin ratio; MIBC, muscle-invasive bladder cancer; NLR, neutrophil-to-lymphocyte ratio; NMIBC, non-muscle invasive bladder cancer; PLR, platelet-to-lymphocyte ratio; PNI, prognostic nutritional index.