Table 5.
CYP2D6 haplotype distribution in the two groups studied (Case and Control) and their association with the no benefit/benefit status
| Allele | Case (frequency) | Control (frequency) | OR | 95% Lo | 95% Hi | χ2 | P-value | Common (frequency >1%) |
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| *1 | 20 (37%) | 129 (38%) | 1.000 | 1.000 | 1.000 | 0.092 | 0.761 | + |
| *4 | 7 (13%) | 66 (20%) | 0.730 | 0.291 | 1.831 | 1.157 | 0.282 | + |
| *2 | 9 (17%) | 61 (18%) | 0.973 | 0.415 | 2.282 | 0.077 | 0.782 | + |
| *41 | 6 (11%) | 38 (11%) | 1.045 | 0.387 | 2.817 | 0.001 | 0.971 | + |
| *35 | 3 (6%) | 20 (6%) | 0.921 | 0.248 | 3.429 | 0.040 | 0.841 | + |
| *5 | 1 (2%) | 8 (2%) | 0.678 | 0.079 | 5.829 | 0.159 | 0.690 | + |
| *9 | 3 (6%) | 4 (1%) | 5.760 | 1.111 | 29.870 | 5.358 | 0.021 | + |
| *10 | 0 (%) | 4 (1%) | 0.000 | 0.000 | 0.000 | 0.744 | 0.389 | |
| *2N | 2 (4%) | 3 (1%) | 4.795 | 0.710 | 32.380 | 3.142 | 0.076 | + |
| *1N | 0 (%) | 2 (1%) | 0.000 | 0.000 | 0.000 | 0.000 | 1.000 | |
| *6 | 3 (6%) | 1 (0%) | 81.340 | 3.356 | 1,971.000 | 19.400 | 0.011 | + |
| *15 | 0 (%) | 1 (0%) | 0.000 | 0.000 | 0.000 | 0.000 | 1.000 | |
| *35 | 0 (%) | 1 (0%) | 0.000 | 0.000 | 0.000 | 0.000 | 1.000 | |