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. 2018 Oct 24;13:6699–6715. doi: 10.2147/IJN.S178809

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© 2018 Dhakal et al. This work is published and licensed by Dove Medical Press Limited

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Virus-specific HI and secretary IgA antibody responses in vaccinated and virus-challenged pigs at DPC 6.

Notes: BAL fluid samples were analyzed for HI titers against (A) SwIAV H1N1-OH7; (B) H1N2-OH10 (heterologous to challenge virus); and (C) H3N2-OH4 (heterosubtypic to challenge virus). Likewise, mucosal IgA antibody response in nasal swab was determined by ELISA against (D) H1N1-OH7; (E) H1N2-OH10; and (F) H3N2-OH4 IAVs. HI titers are shown in geometric mean ±95% CI. Data were analyzed by non-parametric Kruskal–Wallis test followed by Dunn’s post hoc test. Asterisk refers to statistical difference between two indicated pig groups (*P<0.05 and **P<0.01).

Abbreviations: BAL, bronchoalveolar lavage; DPC, day post-challenge; HI, hemagglutination inhibition; NPs, nanoparticles; SwIAV, swine influenza A virus.