Table 2.
Top 10 most downregulated differentially expressed miRNAs between DR group and DS group of human breast cancer
| MiRNA | Average expression in DR group | Average expression in DS group | FC | log2FC | P-value |
|---|---|---|---|---|---|
|
| |||||
| hsa-miR-1253 | 0.9842 | 6.6550 | 0.147889 | –2.75742 | 0.0442 |
| hsa-miR-584-5p | 1.6060 | 9.7650 | 0.164465 | –2.60415 | 0.0290 |
| hsa-miR-520b | 0.7801 | 4.5860 | 0.170105 | –2.55551 | 0.0215 |
| hsa-miR-1245b-5p | 0.6776 | 3.4550 | 0.196122 | –2.35018 | 0.0336 |
| hsa-miR-711 | 0.5090 | 2.5880 | 0.196677 | –2.34610 | 0.0407 |
| hsa-miR-92a-1-5p | 1.0600 | 5.2480 | 0.201982 | –2.30770 | 0.0267 |
| hsa-miR-663b | 0.9303 | 4.4860 | 0.207379 | –2.26966 | 0.0184 |
| hsa-miR-617 | 1.9690 | 9.3850 | 0.209803 | –2.25289 | 0.0447 |
| hsa-miR-922 | 0.6251 | 2.8600 | 0.218566 | –2.19386 | 0.0208 |
| hsa-miR-586 | 1.4700 | 6.6050 | 0.222559 | –2.16774 | 0.0188 |
Abbreviations: DR, drug resistant; DS, drug sensitive; FC, fold change.