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. 2018 Oct 24;10:4891–4898. doi: 10.2147/CMAR.S180695

Table 2.

Cox analysis for disease-free survival in 281 patients with triple-negative breast cancer

Variables Univariate analysis
Multivariate analysis
HR 95% CI P-value HR 95% CI P-value

Age (years)
 >50 vs ≤50 0.69 0.56–1.09 0.196 0.69 0.51–1.18 0.105
Type of surgery
 Radical mastectomy vs breast conserving surgery 1.05 0.91–1.12 0.244 0.92 0.84–1.24 0.379
Tumor stage
 T2–4 vs T1 1.69 1.16–2.59 0.006 1.50 1.31–2.49 0.015
Lymphovascular invasion
 Yes vs no 1.24 1.09–1.76 0.021 1.01 0.92–1.26 0.152
Histological grade
 III vs I–II 2.31 1.92–3.16 <0.001 2.01 1.35–2.59 0.011
Lymph node status
 Yes vs no 1.94 1.46–2.38 0.004 1.19 1.16–1.86 0.059
Adjuvant radiotherapy
 Yes vs no 0.77 0.69–1.12 0.587 0.72 0.64–1.07 0.659
Chemotherapy
 Neoadjuvant vs adjuvant 0.84 0.72–1.15 0.489 0.77 0.69–1.12 0.575
dNLR
 ≥2.6 vs <2.6 2.39 1.85–2.59 <0.001 1.90 1.52–2.46 0.007

Abbreviation: dNLR, derived neutrophil-to-lymphocyte ratio.