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. 2018 Oct 24;13:6809–6827. doi: 10.2147/IJN.S177993

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© 2018 Qiu et al. This work is published and licensed by Dove Medical Press Limited

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In vivo antitumor efficiency.

Notes: (A) Body weight of BXPC-3 tumor-bearing nude mice after different treatments. (B) The tumor volume of tumor-bearing nude mice after different treatments. (C) Tumor weight after different treatments. (D) Photographs of the tumor from different treatment groups after 14 days. (E) IHC assays for Bcl-2 and cleaved-Casp3 expression, (F) the relative expression of Bcl-2 and (G) caspase-3 relative expression. *P<0.05, for vs all the other treatments.

Abbreviations: Cleaved-Casp3, cleaved-caspase-3; GEM, gemcitabine; IHC, immunohistochemistry; NC, negative control; ORI, oridonin; ORI-NPs, Gd-ORI@HAuNCs- Cy7 nanoparticles; ORI-GPC1-NPs, GPC1-Gd-ORI@HAuNCs-Cy7 nanoparticles.