Table 2. Durations from ketamine/xylazine injection until the behavioral marker as well as between defined markers.
| Time in minutes (median and 1st and 4th quartile) | ||||
|---|---|---|---|---|
| ATI | ATI+PRA | AUC | p* | |
| Time to Marker | ||||
| RORR | 25.9 [24.6–27.4] | 26.1 [18.2 52.1] | 0.57 [0.20 0.93] | p = 0.7922 |
| Sticky Dot Notice | 36.1 [26.1–40.4] | 60.8 [33.3 81.7] | 0.73 [0.33 1] | p = 0.2468 |
| Time between Markers | ||||
| 1st behavior and RORR | 8.1 [7.2–10.3] | 9.3 [1.3 34.9] | 0.53 [0.13 0.90] | p = 0.8918 |
| RORR to Sticky Dot | 8.8 [1.2–15.0] | 25.4 [13.2 54.5] | 0.93 [0.73 1] | p = 0.0173 |
ATI: atipamezole; PRA: prazosin; RORR: return of righting reflex
* p-values were calculated using the Mann-Whitney U test; AUC: area under the receiver operating curve; AUC was used as effect size