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Structures of copper bis(thiosemicarbazone) complexes and PET imaging with 64Cu and its bis(thiosemicarbazone) complexes in mice 30 min post injection. Cu-acetate is rapidly taken up in liver and excreted into the gut; CuATSM (hypoxia-selective tracer) behaves in a superficially similar way; CuGTSM (non-hypoxia-selective tracer) likewise shows liver and gut activity but also shows high uptake in normal brain and myocardium.
