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. 2018 Oct 29;13(10):e0206685. doi: 10.1371/journal.pone.0206685

Table 1. Chi-square test results for ALDH1 and CD44 expression score based on the staining area and intensity of color reaction.

Normal
no. (%)
EH
no. (%)
AH
no. (%)
EC
no. (%)
p a value
ALDH1 <0.001
Low 40 (95.24) 40 (83.33) 37 (88.10) 63 (55.75)
High 2 (4.76) 8 (16.67) 5 (11.90) 50 (44.25)
CD44 <0.001
- (negative) 40 (95.24) 47 (97.92) 40 (95.24) 73 (64.60)
+ (positive) 2 (4.76) 1 (2.08) 2 (4.76) 40 (35.40)
Combination of ALDH1 & CD44 <0.001
ALDH1Low & CD44 38 (90.48) 39 (81.25) 36 (85.71) 44 (38.94)
(ALDH1Low & CD44+)+(ALDHHigh & CD44) 4 (9.52) 9 (18.75) 5 (11.90) 48 (42.48)
ALDH1High & CD44+ 0 (0) 0 (0) 1 (2.38) 21 (18.58)

Normal: normal endometrium; EH: endometrial hyperplasia without atypia; AH: atypical hyperplasia; EC: endometrial carcinoma.

a Fisher’s exact test.