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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Hypertension. 2018 Oct;72(4):862–869. doi: 10.1161/HYPERTENSIONAHA.118.11499

Table 1.

Main characteristics of selected studies using ambulatory blood pressure monitoring

Patients MUCH Definition FU (years) Events Type of Event
Study CH MUCH CH MUCH
OvA Study 20037 146 143 Day BP≥135/85 mmHg 5 7 9 Fatal/Nonfatal CVE
Chieti-Pescara Study 2005–201710,26 523 215 Day BP≥135/85 mmHg 10 79 69 Fatal/Nonfatal CVE
IDACO Study 2005–20179,12,13,15,18,19,23 528 236 Day BP≥135/85 mmHg 11 147 93 Fatal/Nonfatal CVE
Hadassah Study 200816 360 268 Day BP≥135/85 mmHg 7.7 23 29 All-Cause Mortality
Jackson Heart Study 201624 272 135 Day BP≥135/85 mmHg 8.2 16 22 Fatal/nonfatal CVE
Spanish Registry Study28 7406 2378 Day BP≥135/85 mmHg 4.7 273 166 All-Cause Mortality

BP, blood pressure; CH, controlled hypertension; CVE, cardiovascular events (stroke, coronary artery disease, heart failure and peripheral revascularization for OvA, Chieti-Pescara and IDACO Studies; stroke and coronary artery disease for Jackson Heart Study); FU, follow-up (mean); IDACO, International Database on Ambulatory blood pressure in relation to Cardiovascular Outcomes; MUCH, masked uncontrolled hypertension; OvA, Office versus Ambulatory pressure. Data of the OvA, IDACO, Hadassah and Spanish Registry Studies are provided by the authors. Data of the Chieti Pescara Study, provided by the authors, come from the overall database of treated hypertensive patients at baseline (2264 patients) which includes patients aged≥60 years reported in Ref. 26, those aged < 60 years reported in Ref. 10 and other patients aged < 60 years of the database (data of patients aged≥and < 60 years are equally updated to 2013); the cutoff of daytime BP to define MUCH was chosen for homogeneity with other studies. Data of the Jackson Heart Study are published data. Daytime BP recording interval: OvA Study (30 minutes), Chieti-Pescara Study (15 minutes), IDACO Study (15–30 minutes), Hadassah Study (20 minutes), Jackson Heart Study (20 minutes) and Spanish Registry Study (20 minutes).