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. Author manuscript; available in PMC: 2019 Aug 21.
Published in final edited form as: Circulation. 2018 Aug 21;138(8):823–835. doi: 10.1161/CIRCULATIONAHA.118.033597

Figure 2.

Figure 2

Simplified algorithm for PA screening and triaging based primarily on plasma renin and secondarily on serum aldosterone. Aldo, aldosterone; BP, blood pressure; CVA, cerebrovascular accident; DRC, direct renin concentration; FH, family history; MR, mineralocorticoid receptor; PA, primary aldosteronism; PRA, plasma renin activity. Patients with low renin and aldosterone >10 ng/dL are referred for confirmatory testing and subtyping; most patients with aldosterone >20 ng/dL have PA, and those with hypokalemia do not require confirmatory testing.