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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Stroke. 2018 Oct;49(10):2453–2463. doi: 10.1161/STROKEAHA.118.021452

Figure 1. The db/db mice exhibit impaired sensorimotor performance but similar cognitive functions compared to db/+ mice and WT mice up to 35d after dMCAO.

Figure 1.

A, Post-stroke mortality rates were higher in db/db mice than WT and db/+ mice. Note that the data points for the db/+ mice (blue triangles) overlap those of the WT mice (black circles). Logrank test. n=12–13/group. B, The blood sugar levels of db/db mice were significantly higher than WT and db/+ mice. n=8/group. C, Sensorimotor functions were evaluated by the adhesive removal test. The latencies to contact and remove the tape were recorded. n=6/sham group. n=8–12/dMCAO group. D, In the open field test, total distances travelled in the arena and the time spent in the central area of the open field was recorded. n=4/sham group. n=8–12/dMCAO group. *p<0.05, **p<0.01, ​***p<0.001, WT vs. db/db; +p<0.05, ++p<0.01, +++p<0.001, WT vs. db/+; #p<0.05, ##p<0.01, ​###p<0.001, db/+ vs. db/db; two-way repeated measures ANOVA followed by the Bonferroni post hoc. Both main effects and pairwise comparisons (with corrections) are displayed.