Table 3:

Selected clinical and laboratory values (paired samples)

Parameter	Usual Care				DASH/SRD				Between group difference DASH/SRD vs. Usual Care
	Discharge	Week 4	p	Within group change	Discharge	Week 4	p	Within group change	p	Estimate (SE) or Log Effect (%)
Systolic blood pressure (mmHg)	123±22	123±22	0.99	0±20	126±22	121±19	0.17	-5±18	0.46	-3.6 (4.8)
Serum potassium (mmol/L)	4.3±0.4	4.2±0.5	0.84	0.0±0.5	4.3±0.4	4.3±0.7	0.98	0.0±0.8	0.60	0.09 (0.16)
Serum creatinine (mg/dL)	1.4±0.4	1.3±0.5	0.53	0.0±0.3	1.4±0.4	1.4±0.4	0.49	0.0±0.3	0.87	0.01 (0.08)
BNP (pg/mL)*	190 (125,624)	237 (143,917)	0.44	61 (−94,133)	176 (68,501)	232 (112,606)	0.041	36 (−13,169)	0.59	11% higher*
hs-Troponin I (pg/mL)*	162 (76,362)	183 (76,347)	0.84	-7.5 (−30,76)	150 (109,230)	131 (74,219)	0.025	-21 (−65,31)	0.23	20% lower*
C-reactive protein (mg/L)*	14.2 (5.4,28.5)	5.2 (2.8,9.2)	0.001	-6.6 (−19.3,−2.0)	6.2 (4.6,14.3)	4.9 (1.5,9.0)	0.10	-0.9 (−3.9,0.5)	0.35	37% higher*
Prealbumin (mg/dL)	21.2±6.3	25.9±8.3	0.008	4.7±7.1	23.2±6.6	25.6±6.5	0.025	2.5±5.2	0.36	-1.6 (1.8)

Abbreviations: BNP; B-type natriuretic peptide; hs-troponin I; high sensitivity troponin I. Within-group changes are Week 4 minus Discharge, with values expressed as mean ± standard deviation, or median (interquartile range) for log-transformed variables.

^*Statistical tests were performed on the log scale for BNP and hs-Tropopnin I and on the log(x+1) scale for C-reactive protein; all transformations were made due to skewness. Estimates are presented on the percent scale (approximate percent scale for C-reactive protein). Because confidence intervals are asymmetrical and thus SEs are not useful, we present 95% confidence intervals for estimates: BNP (−25% lower to 55% higher); hs-Troponin I (43%lower to 14% higher); C-reactive protein (29% lower, 162% higher)