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. 2018 Oct 23;11:7323–7331. doi: 10.2147/OTT.S173391

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© 2018 Liu et al. This work is published and licensed by Dove Medical Press Limited

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A lung SCC patient was identified as harboring ERBB2 20ins and responded to afatinib.

Notes: (A) Hematoxylin–eosin staining revealed the histological appearance of SCC. The green arrow and a green circle indicate typical histological appearance of SCC. (B) Responses of an ERBB2 20ins patient with lung SCC to afatinib. Computed tomography scans of the chest were obtained at baseline and after 3 months treatment of afatinib. The red arrows indicate tumor lesion.

Abbreviations: 20ins, exon 20 insertions; SCC, squamous cell carcinoma.