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. 2018 Oct 23;11:7333–7343. doi: 10.2147/OTT.S167872

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© 2018 Gao et al. This work is published and licensed by Dove Medical Press Limited

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Down-expression of CXCL11 inhibits EMT of SW480 cell.

Notes: (A) SW480 cells were transfected with siCon or siCXCL11 and the expression of epithelial marker E-cadherin and mesenchymal markers (N-cadherin and fibronectin) were examined by indirect immunofluorescence assay. Magnification ×200, scale bar represents 100 µm. (B) The expression of the EMT markers in SW480 cells was determined by western blotting analysis. (C) SW480 cell was transiently transfected with siCon or siCXCL11, and the mRNA level of EMT-associated markers was detected by qRT-PCR. **P<0.01 compare to control cell.

Abbreviations: EMT, epithelial-mesenchymal transition; GADPH, Glyceraldehyde 3-phosphate dehydrogenase; qRT-PCR, quantitative real-time PCR; siCXCL11, siRNA CXCl11; EMT, epithelial-mesenchymal transition; siCon, siRNA Control; siCXCL, small interfering RNA targeting C-X-C motif chemokine 11.