Table 3. Outcome of studies assessing normal anastomoses; HBOT− hyperbaric oxygen treatment; Prob. − probability; ALF − anastomotic line fibrosis; U − unknown; MMP − matrix-metalloproteinase; ns − not significant; ↑ − significantly increased; ↓ − significantly decreased; NV – neovascularization; CD − collagen deposition; N – necrosis; E – epithelialization; G – granulation; FML − formation of mucosal layer; SI − severity of inflammation; tMDA − tissue malondialdehyde; tMPO − tissue myeloperoxidase; tSOD − tissue superoxide dismutase; tGSH-Px − tissue glutathionperoxidase; sMDA − serum malondialdehyde; sNO − serum nitric oxide; sCAT − serum catalase; tNO − tissue nitric oxide; tCAT − tissue catalase .
| Author | Bursting pressure(mmHg) | Hydroxyproline | Pathology | Other | Improved | |||||
| HBOT | Control | P≤0.05 | HBOT | Control | Units | P≤0.05 | ||||
| Hamzaoğlu[20] | 123±18.4 | 104±18.9 | Yes | 10.12±4 | 7.4±2 | mg·mg tissue-1 | Yes | − | − | Yes |
| Erenoglu[21] | 221±6.05 | 190.2±18.14 | No | 22.88±2.38 | 9.01±2.04 | µg·10 mg tissue-1 | Yes | − | − | No |
| Yagci[23] | 115.5±21.1 | 107.2±37.5 | No | 13.89±3.43 | 9.95±2.65 | µM· mg tissue-1 | Yes | ALF ns | − | No |
| Yagci[23] | 113.6±16.9 | 107.2±37.5 | No | 13.11±4.39 | 9.95±2.65 | µM· mg tissue-1 | Yes | ALF ns | − | No |
| Yagci[23] | 119.2±16.7 | 107.2±37.5 | No | 13.25±3.27 | 9.95±2.65 | µM· mg tissue-1 | Yes | ALF ns | − | No |
| Azevedo[25] | − | − | − | Unknown | Unknown | µg· mg tissue-1 | Yes | − | MMP1 ns; MMP9 ns | Yes |
| Adas[27] | 93.3±20.5 | 81.4±20.1 | Yes | − | − | − | − | CD↑; NV↑; N ns; E ns; G ns | − | Yes |
| Kemik[28] | 93.4±24.8 | 84.5±24.4 | No | − | − | − | − | NV↑; CD ns; N ns; E ns; G ns | − | No |
| Yildiz[29] | 133.7±29.7 | 110.7±18.6 | No | 17.3±6.6 | 15±5.8 | µM·mg-1 tissue-1 | No | ALF ns | − | No |
| Poyrazoglu[30] | 152.9±18 | 122.6±16.7 | Yes | 83±11.1 | 60.4±14.4 | mg·g protien-1 | Yes | − | tMDA↓; tMPO↓; tSOD↑; tGSH-Px↑ | Yes |
| Poyrazoglu[30] | 126±13.6 | 122.6±16.7 | No | 63.7±18.7 | 60.4±14.4 | mg·g protien-1 | No | − | tMPO↓; tMDA ns; tSOD ns; tGSH-Px ns | No |
| Boersema[4] | 162.4±39.7 | 141.1±73.3 | No | − | − | − | − | NV↑; CD206+↑; M2/M1↑; CD ns; iNOS+ ns | − | Yes |
| Emir[31] | 213±27 | 197±9.1 | No | 26.5±4.1 | 26.8±4.36 | µg·10 mg tissue-1 (dry) | No | FML ns; SI ns | sMDA↓; sNO ns; CAT ns; tMDA ns; tNO ns; tCAT ns | No |