Table 4. Outcome of studies assessing ischemic anastomoses; HBOT− hyperbaric oxygen treatment; ALF− anastomotic line fibrosis; ns − not significant; MMP − matrix-metalloproteinase; ↑ − significantly increased; ↓ − significantly decreased; CD − collagen deposition; NV – neovascularization; N – necrosis; E – epithelialization; G − granulation .
| Author | Bursting pressure(mmHg) | Hydroxyproline | Pathology | Other | Improved | |||||
| HBOT | Control | Prob. ≤ 0.05 | HBOT | Control | Units | Prob. ≤ 0.05 | ||||
| Hamzaoğlu[20] | 102.2±14.8 | 77.5±22.1 | Yes | 6.04±2 | 4.76±2 | mg·mg tissue-1 | Yes | − | Yes | |
| Guzel[22] | 104±19.4 | 69.5±16.7 | Yes | 12.1±1.1 | 4.3±0.6 | mg·100 mg wet tissue-1 | Yes | − | Yes | |
| Yagci[23] | 81.2±9.2 | 79.3±7.7 | No | 9.51±.87 | 8.42±2.1 | µM·mg tissue-1 | No | ALF ns | − | No |
| Yagci[23] | 97.9±17.9 | 79.3±7.7 | Yes | 10.01±1.88 | 8.42±2.1 | µM·mg tissue-1 | No | ALF ns | − | Yes |
| Yagci[23] | 109.0±8.4 | 79.3±7.7 | Yes | 11.06±1.95 | 8.42±2.1 | µM·mg tissue-1 | Yes | ALF ns | − | Yes |
| Azevedo[25] | − | − | − | Unknown | Unknown | µM·mg tissue-1 | No | − | MMP1↑; MMP9↑ | Yes |
| Adas[27] | 109.9±25.3 | 62±21.19 | Yes | − | − | − | − | CD↑; NV↑; N↓; E ns; G ns | − | Yes |