Table 4.

Hazard ratios for worsening disability by percent weight change from baseline in Forward and VARA, adjusting for enrollment BMI.

	Risk of Worsening Disability Forward		Risk of Worsening Disability VARA
	HR (95% CI)	p	HR (95% CI)	p
No Weight Loss	Ref	--	Ref	--
>5% Loss of BMI	1.10 (1.03, 1.17)	0.004	1.24 (0.98, 1.57)	0.07
>10% Loss of BMi	1.23(1.14, 1.33)	<0.001	1.52 (1.12, 2.06)	0.007

Forward: Model adjusted for age, sex, race, enrollment BMI, RDCI, current smoking and follow-up time in the registry.

VARA: Model adjusted for age, sex, race, enrollment BMI, RDCI, CRP, swollen joint count, current smoking, and follow-up time in the registry.

Abbreviations: Forward= National Data Bank for Rheumatic Diseases; VARA= Veterans Affairs Rheumatoid Arthritis Registry; HR= Hazard Ratio; BMI= Body Mass Index; RDCI= Rheumatic Disease Comorbidity Index; CRP= C-Reactive Protein