Fig. 4. 6-Shogaol down-regulated NF-κB signaling.

6-Shogaol significantly inhibited activation and regulated the inhibitor kinases of NF-κB signaling (a). Representative Immunoblot exhibiting the influence of 6-shogaol on the expressions of proteins (b and c). Relative expression of proteins. Values are represented as mean±SD, n=6. p<0.05 as determined by one-way ANOVA followed by DMRT analysis. Relative expressions of proteins from different experimental groups with control expressions set at 100%. ^*Represents p<0.05 vs. control; ^#Represents p<0.05 vs. EMS control. ^a–eRe presents mean values from different experimental groups that differ from each other at p<0.05.