Table 1.
CD4 count | CD4/CD8 | ||||||
---|---|---|---|---|---|---|---|
IDa | Time to cART (months)b | Time on cART (months)c | Pre-treatment Viral Loadd,e | Before cARTd,f | On cARTf,g | Before cARTd,f | On cARTf,g |
DT1 | 50 | 22 | 48526 | 383 | 524 | 0.72 | 1.35 |
DT2 | 22 | 18 | 132317 | 324 | 297 | 0.46 | 0.52 |
DT3 | 8 | 18 | 125716 | 391 | 711 | 0.48 | 0.65 |
DT4 | 11 | 5 | 27244 | 465 | 535 | 0.45 | 0.74 |
DT5 | 25 | 5 | 4612 | 408 | 739 | 0.48 | 1.00 |
DT6 | 19 | 15 | 66929 | 246 | 501 | 0.24 | 0.62 |
DT7 | 50 | 5 | 15297 | 330 | 468 | 0.42 | 0.77 |
DT8 | 5 | 12 | >500000 | 279 | 528 | 0.26 | 0.72 |
DT9 | 21 | 14 | 28288 | 184 | 579 | 0.30 | 0.88 |
DT10 | 13 | 20 | 1702 | 357 | 563 | 0.44 | 0.72 |
DT11 | 22* | 12 | 10033 | 819 | 819 | 0.88 | 1.36 |
DT12 | 9 | 8 | 111893 | 629 | 880 | 0.85 | 1.53 |
ET1 | 2 | 14 | >500000 | 627 | 594 | 0.66 | 0.89 |
ET2 | 4 | 18 | 283441 | 187 | 522 | 0.20 | 0.88 |
ET3 | 1 | 11 | 36338 | 768 | 1099 | 1.18 | 1.83 |
ET4 | 3 | 14 | 17292 | 612 | 1342 | 0.33 | 1.32 |
ET5 | 3 | 15 | 20106 | 787 | 829 | 1.06 | 1.69 |
ET6 | 2 | 18 | >500000 | 421 | 854 | 0.31 | 1.89 |
ET7 | 1 | 13 | >500000 | 435 | 942 | 0.13 | 1.52 |
ET8 | 3 | 12 | 172468 | 435 | 657 | 0.59 | 1.16 |
ET9 | 3 | 17 | 26547 | 400 | 728 | 0.70 | 1.79 |
ET10 | 3* | 11 | 231360 | 330 | 1080 | 0.18 | 1.24 |
ET11 | 2 | 12 | >500000 | 654 | 1026 | 0.42 | 1.47 |
ET12 | 4 | 16 | >500000 | 339 | 691 | 0.08 | 0.66 |
ET13 | 4 | 12 | >500000 | 213 | 386 | 0.19 | 0.81 |
DT, Delayed Treatment Group; ET, Early Treatment Group.
Relative to the presumed date of infection.
Time from the moment of cART initiation to sample obtaining.
Determinations evaluated at the closest sample obtained before cART initiation.
Versant HIV-1 RNA 3.0 assay, Siemens. Lower and upper detection limits are 50 and 500,000 RNA copies/ml, respectively (1.7 and 5.7 log10).
Determined by flow cytometry.
Determinations evaluated in samples used in this study.
Estimated time to cART initiation, as informed by the clinician.