Table 3.

Percutaneous cerebral protection devices currently under development or first-in-man study stage.

	Emblock	Point-Guard	Emboliner	ProtEmbo	Embolisher	Fliterlex
Device Illustration
Company	Innovative Cardiovascular Solutions	Transverse Medical	Cardiological Solutions	Protembis	Cardioptimus	Fliterlex
Regulatory status	Feasibility study ongoing	Pre-clinical	Pre-clinical	Feasibility study awaited	Pre-clinical	Pre-clinical
Access	12F Contralateral Transfemoral	Unclear (Assume femoral)	9F Contralateral Transfemoral	6F left Transradial	Contralateral Transfemoral	Ipsilateral Transfemoral
Embolic protection mechanism	Capture and removal	Deflector, capture and removal	Capture and removal	Deflector	Deflector	Deflector
Cerebral Protection	All supra-aortic arteries	All supra-aortic arteries	All supra-aortic arteries	All supra-aortic arteries	All supra-aortic arteries	All supra-aortic arteries
Positioning	Aortic Arch	Aortic arch	Aortic arch	Aortic arch	Aortic arch	Aortic arch and descending aorta
Other features	• Integrated pigtail catheter • Designed to minimize use of contrast	• Sealing technology • Conforms to aortic arch	• Dual-layer Nitinol mesh filter mounted on a 6-Fr catheter	• Deflection of microparticles as tiny as 60 microns to descending aorta		• Full protection: Brain, Aorta and Body (kidney)