Table 1.
Summary of drug treatments during the main trial.
| Days | Time | Treatment group |
||
|---|---|---|---|---|
| Anxious (n = 18) | Depressed (n = 16) | Control (n = 16) | ||
| 1 | 4 PM | Saline (i.p.) | pCPA (i.p.) | Saline (i.p.) |
| 2–5 | 8 AM | Saline (i.p.) | pCPA (i.p.) | Saline (i.p.) |
| 4 PM | Saline (i.p.) | pCPA (i.p.) | Saline (i.p.) | |
| 5 | 4 PM | iButtons inserted and cohesive bandages applied to all animals | ||
| 6 | 8 AM | Saline (i.p.) | pCPA (i.p.) | Saline (i.p.) |
| 30 min prior to attention bias test | mCPP (i.m.) | Saline (i.m.) | Saline (i.m.) | |
| 30 min post injection | Attention bias testing for all animals | |||
The pharmacological agent and administration method are given for each treatment group at each time point. All sheep received a total of 10 intraperitoneal injections during days 1 to 6 and one intramuscular injection on day 6, 30 min prior to undergoing the attention bias test.