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. 2018 Oct 23;9:2417. doi: 10.3389/fimmu.2018.02417

Figure 5.

Figure 5

Mtb preferentially activates MAPK and NF-κB in MDSCs. Protein levels of p38, ERK1/2, JNK, and NF-κB and their phosphorylated counterparts at various time points post Mtb infection (MOI 20) (A,B) or LPS stimulation (25 ng/ml) (C). Densitometry of the western blots was performed using ImageJ, values are plotted and normalized using actin. Data are representative of 2 independent experiments (n = 3–5 individuals) (A, B, Mtb D), 3 independent experiments (n = 3–7 individuals) (C, LPS D). Each symbol corresponds to a single donor, shown are median ± IQR, paired Student's t-test, *p ≤ 0.05, **p ≤ 0.01.