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. 2018 Oct 29;8:15976. doi: 10.1038/s41598-018-34321-x

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effects of glutamine and SDMA peak areas on fearfulness in Great Danes and German Shepherds. (a) Association between glutamine peak area and fearfulness in Great Danes. The higher the glutamine amount is, the higher is the dog’s probability of being fearful when the dog is Great Dane. (b) Association between glutamine peak area and fearfulness in German Shepherds. The higher the glutamine amount is, the higher is the dog’s probability of being fearful when the dog is German Shepherd. (c) Association between SDMA peak area and fearfulness in Great Danes. The higher the SDMA amount is, the higher is the dog’s probability of being fearful when the dog is Great Dane. (d) Association between SDMA peak area and fearfulness in German Shepherds. SDMA has a slight, non-significant negative association with fearfulness when the dog is German Shepherd. Dashed lines indicate 95% confidence limits. SDMA, symmetric dimethylarginine.