Table 1.
Demographical and clinical data of the study population.
| Characteristic | All (n = 1482) | Rapid progressors (n = 342) | Non-rapid progressors (n = 1140) | P-value* |
|---|---|---|---|---|
| Women | 669 (45.14) | 149 (43.57) | 520 (45.61) | <0.001 |
| Diabetes mellitus | 1104 (74.50) | 331 (96.78) | 773 (67.81) | <0.001 |
| Age, years | 51.59 ± 14.74 | 55.59 ± 12.49 | 50.38 ± 15.16 | <0.001 |
| Systolic pressure, mmHg | 129.25 ± 15.42 | 133.69 ± 14.76 | 127.96 ± 15.37 | <0.001 |
| Diastolic pressure, mmHg | 77.06 ± 8.77 | 76.38 ± 8.93 | 77.26 ± 8.72 | 0.29 |
| eGFR (CKD-EPI), ml/min/1.73 m2 | 69.28 ± 19.50 | 66.04 ± 24.79 | 70.25 ± 17.50 | 0.46 |
| eGFR < 60 ml/min/1.73 m2 | 361 (24.35) | 124 (36.26) | 237 (20.79) | <0.001 |
| UAE, mg/24 h | 236.82 ± 708.20 | 672.13 ± 1183.44 | 106.23 ± 398.58 | <0.001 |
| UAE > 30 mg/24 h | 288 (19.43) | 145 (42.40) | 143 (12.54) | 0.98 |
| eGFR < 60 ml/min/1.73 m2 or UAE > 30 mg/24 h | 430 (29.01) | 152 (44.44) | 278 (24.39) | <0.001 |
| CKD273 score | −0.1848 ± 0.56 | 0.1619 ± 0.56 | −0.2888 ± 0.51 | <0.001 |
| Follow-up, years | 3.24 ± 1.18 | 2.48 ± 1.06 | 3.46 ± 1.12 | <0.001 |
| eGFR datapoints | 4.54 ± 2.09 | 5.28 ± 1.97 | 4.32 ± 2.08 | <0.001 |
Data expressed as n (%) or mean ± standard deviation. *P-values were calculated using Mann-Whitney test for continuous variables and ANOVA test for dichotomous variables. CKD273: urinary peptidomics classifier. UAE: urinary albumin excretion.