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. 2018 Oct 29;8:15917. doi: 10.1038/s41598-018-34166-4

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Ido2 inhibits the cytokine signalling. (a) Heat maps representing the relative expression of the signalling pathways in RAW-MOC and RAW-Ido2 cells. (b) The protein expression of stat3 in RAW-MOC and RAW-Ido2 cells. (c) qRT-PCR analysis of LPS induced and stat3-relative gene expression in RAW-MOC and RAW- Ido2 cells. Data are presented as the mean ± SD (n = 3 each). *p < 0.05.