Cumulative proportions of first recurrences after treatment of the initial Plasmodium vivax infection in the current study (A) compared with historical data from US soldiers returning from the Pacific [14] (B), Indonesian soldiers returning from Papua, Indonesia [15, 16] (C), and children aged 1–5 years living in East Sepik Province, Papua New Guinea [17] (D). Note that the cumulative recurrence curve of more slowly eliminated schizonticides (ie, chloroquine, dihydroartemisinin-piperaquine) is shifted to the right, compared with rapidly eliminated schizonticides (ie, artesunate). Permission to use (C) was obtained from the last author and the figure is also under Creative Commons CC-BY license. Permission to use (D) was obtained by Oxford University Press, licence number 4241781058637. Abbreviations: AS, artesunate; AS-PYR, artesunate-pyronaridine; DHA-PP, dihydroartemisinin-piperaquine; PMQ, primaquine.