Table 1.
Description of First Plasmodium vivax Recurrence
| Treatment Arm | No. | First Recurrence by 1 y, No. (%; 95% CI) |
Median Time to First Recurrence, da, (IQR; Range) | Recurrence by Day 28, No. (%) | Cumulative Risk of Recurrence by Day 28b, OR (95% CI) | P Value |
|---|---|---|---|---|---|---|
| AS | 224 | 177 (79; 73–84) | 28 (21–42; 7–252) | 112 (50) | Comparator | |
| CQ | 222 | 165 (74; 68–80) | 49 (35–74; 13–354) | 18 (8.1) | 0.088 (.051–.153) | <.001 |
| CQ + PMQ | 198 | 35 (18; 13–24) | 195 (82–281; 13–364) | 1 (0.5) | 0.005 (.001–.037) | <.001 |
Abbreviations: AS, artesunate; CI, confidence interval; CQ, chloroquine; IQR, interquartile range; OR, odds ratio; PMQ, primaquine.
aNonparametric K-sample test was used to compare medians between groups; all P values < .001.
bLogistic regression was used to compare the difference between groups.