Table 3.

Comparison of Adverse Events Between Treatment Arms

Adverse Event	No. (%)	RR Ratio (95% CI)	P Valueb
Abdominal pain
AS	10/207 (5)	0.52 (.20–1.37)	.184
CQ	5/223 (2)	0.24 (.08–.74)	.013
CQ + PMQ	8/90 (9)	Comparator	NA
Treatment for anemiaa
AS	4/207 (2)	0.18 (.05–.59)	.005
CQ	7/223 (3)	0.29 (.11–.81)	.018
CQ + PMQ	9/90 (10)	Comparator	NA

Abbreviations: AS, artesunate; CI, confidence interval; CQ, chloroquine; NA, not applicable; PMQ, primaquine; RR, relative risk.

^aAnemia was defined as a hematocrit <30% (<33% if <2 years old).

^bLogistic regression was used to compare differences between groups.