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H3-specific immunoglobulin G (IgG) affinity in ferrets with different exposure histories. Sera were collected from ferrets infected with HK (A), SWZ/HK (B), TX/SWZ/HK (C), or 175C/TX/SWZ/HK (D). Purified ferret IgG was assessed and analyzed for hemagglutinin-specific binding affinity using nonlinear regression (curve fit). Please see the Figure 2 legend for descriptions of influenza virus strains. Abbreviations: HA, hemagglutinin; IgG, immunoglobulin G; OD, optical density.
