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. 2018 Oct 23;8:465. doi: 10.3389/fonc.2018.00465

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Copyright © 2018 Kim, Chung, Kim, Lee, Kim, Bae, Choi and Hewitt.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Hierarchical clustering analysis for immunohistochemical expression of PAUF-associated proteins in cervical cancer patients. (A) Three cluster groups were identified in the present study. Category 1 (n = 118, blue arrow) consists of relatively high AGR2 and POM121 expression. Category 2 (n = 194, red arrow) consists of relatively low AGR2 and PAUF expression. Category 3 (n = 24, green arrow) consists of relatively high PAUF and low POM121 expression. (B) Kaplan–Meier plot for overall survival according to group by hierarchical clustering. A tendency toward decreased overall survival was observed in Category 3 than in the other groups (log-rank test, p = 0.053).