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. 2018 Oct 23;8:468. doi: 10.3389/fonc.2018.00468

Table 3.

Stratification analysis for the association between protective genotypes and neuroblastoma susceptibility.

Variables rs110419 rs4758051 rs10840002 rs2168101 Protective genotypes
AG/GG vs. AA AG/AA vs. GG AG/GG vs. AA GT/TT vs. GG 4–5 vs. 0–3
AOR (95% CI) a Pa AOR (95% CI) a Pa AOR (95% CI) a Pa AOR (95% CI) a Pa AOR (95% CI) a Pa
AGE, MONTH
≤ 18 0.62 (0.42–0.93) 0.020 0.71 (0.47–1.07) 0.099 0.73 (0.48–1.12) 0.147 0.65 (0.44–0.97) 0.034 0.60 (0.40–0.90) 0.013
>18 0.63 (0.44–0.90) 0.011 0.58 (0.41–0.84) 0.003 0.73 (0.51–1.05) 0.089 0.40 (0.27–0.60) <0.0001 0.45 (0.30–0.66) <0.0001
GENDER
Females 0.64 (0.43–0.96) 0.030 0.67 (0.45–1.01) 0.054 0.69 (0.46–1.04) 0.073 0.60 (0.40–0.90) 0.013 0.58 (0.39–0.88) 0.009
Males 0.62 (0.43–0.89) 0.009 0.60 (0.41–0.86) 0.006 0.75 (0.51–1.09) 0.129 0.43 (0.29–0.64) <0.0001 0.46 (0.32–0.68) <0.0001
SITES OF ORIGIN
Adrenal gland 0.99 (0.59–1.67) 0.983 0.71 (0.43–1.18) 0.192 0.73 (0.44–1.23) 0.236 0.60 (0.36–1.00) 0.052 0.72 (0.44–1.20) 0.209
Retroperitoneal 0.46 (0.31–0.67) <0.0001 0.49 (0.34–0.72) 0.0003 0.61 (0.42–0.90) 0.013 0.47 (0.32–0.71) 0.0003 0.41 (0.27–0.62) <0.0001
Mediastinum 0.67 (0.44–1.01) 0.058 0.89 (0.57–1.37) 0.585 1.01 (0.64–1.58) 0.983 0.50 (0.32–0.79) 0.0027 0.55 (0.36–0.86) 0.009
Others 0.71 (0.29–1.73) 0.444 0.50 (0.20–1.21) 0.123 0.55 (0.22–1.34) 0.185 0.47 (0.18–1.23) 0.124 0.46 (0.18–1.22) 0.120
a

Adjusted for age and gender.

The results were in bold if the 95% CI excluded 1 or P < 0.05.