Table 4.

False-positive report probability analysis for the significant findings.

Genotype	Crude OR (95% CI)	Pa	Statistical powerb	Prior probability
				0.25	0.1	0.01	0.001	0.0001
RS110419 A>G
AG vs. AA	0.62 (0.46–0.82)	0.001	0.361	0.009	0.027	0.232	0.753	0.968
GG vs. AA	0.65 (0.44–0.97)	0.034	0.458	0.184	0.403	0.881	0.987	0.999
AG/GG vs. AA	0.63 (0.48–0.82)	0.0006	0.317	0.006	0.017	0.158	0.654	0.950
≤ 18	0.63 (0.42–0.94)	0.022	0.377	0.148	0.343	0.852	0.983	0.998
>18	0.63 (0.44–0.90)	0.011	0.358	0.081	0.209	0.744	0.967	0.997
Females	0.64 (0.43–0.95)	0.025	0.400	0.158	0.361	0.861	0.984	0.998
Males	0.62 (0.43–0.89)	0.009	0.329	0.073	0.190	0.721	0.963	0.996
Retroperitoneal	0.46 (0.32–0.68)	< 0.0001	0.031	0.007	0.020	0.181	0.690	0.957
RS4758051 G>A
AG vs. GG	0.63 (0.47–0.84)	0.002	0.415	0.012	0.036	0.289	0.804	0.976
AA vs. GG	0.68 (0.47–0.99)	0.046	0.547	0.200	0.429	0.892	0.988	0.999
AA vs. GG/AG	0.64 (0.49–0.84)	0.001	0.377	0.009	0.028	0.240	0.761	0.970
>18	0.59 (0.41–0.84)	0.004	0.236	0.045	0.123	0.608	0.940	0.994
Males	0.60 (0.41–0.86)	0.006	0.271	0.061	0.164	0.683	0.956	0.995
Retroperitoneal	0.49 (0.34–0.72)	0.0002	0.054	0.011	0.033	0.270	0.789	0.974
RS10840002 A>G
AG vs. AA	0.68 (0.51–0.92)	0.012	0.666	0.050	0.138	0.637	0.947	0.994
GG/AG vs. AA	0.74 (0.56–0.97)	0.031	0.764	0.109	0.268	0.801	0.976	0.998
Retroperitoneal	0.61 (0.42–0.90)	0.013	0.330	0.103	0.256	0.791	0.974	0.997
RS2168101 G>T
GT vs. GG	0.51 (0.38–0.69)	< 0.0001	0.045	0.001	0.002	0.017	0.146	0.631
TT vs. GG	0.51 (0.28–0.95)	0.034	0.192	0.346	0.614	0.946	0.994	0.999
GT/TT vs. GG	0.51 (0.39–0.68)	< 0.0001	0.035	0.000	0.001	0.007	0.067	0.419
≤ 18	0.66 (0.44–0.98)	0.040	0.470	0.203	0.434	0.894	0.988	0.999
>18	0.40 (0.27–0.60)	< 0.0001	0.008	0.002	0.007	0.074	0.445	0.889
Females	0.62 (0.42–0.93)	0.020	0.363	0.143	0.333	0.846	0.982	0.998
Males	0.43 (0.29–0.64)	< 0.0001	0.016	0.004	0.011	0.113	0.563	0.928
Retroperitoneal	0.48 (0.32–0.72)	0.0004	0.062	0.019	0.055	0.392	0.867	0.985
Mediastinum	0.51 (0.32–0.79)	0.003	0.120	0.068	0.179	0.706	0.960	0.996
PROTECTIVE GENOTYPES
4–5 vs. 0–3	0.52 (0.40–0.69)	< 0.0001	0.042	0.000	0.001	0.009	0.084	0.479
≤ 18	0.61 (0.41–0.91)	0.014	0.320	0.118	0.287	0.816	0.978	0.998
>18	0.45 (0.31–0.66)	< 0.0001	0.027	0.006	0.018	0.171	0.675	0.954
Females	0.60 (0.40–0.90)	0.013	0.300	0.113	0.277	0.809	0.977	0.998
Males	0.46 (0.32–0.68)	< 0.0001	0.033	0.007	0.020	0.181	0.690	0.957
Retroperitoneal	0.41 (0.27–0.62)	< 0.0001	0.014	0.006	0.019	0.173	0.678	0.955
Mediastinum	0.56 (0.36–0.86)	0.009	0.211	0.113	0.277	0.808	0.977	0.998

^aChi-square test was used to calculate the genotype frequency distributions.

^bStatistical power was calculated using the number of observations in the subgroup and the OR and P-values in this table.

The results were in bold if the 95% CI excluded 1 or P < 0.05.