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. 2018 Oct 23;11:385. doi: 10.3389/fnmol.2018.00385

FIGURE 1.

FIGURE 1

Retinal expression pattern of three transgenic mouse lines. (A) Section of an adult mouse retina stained with ToPro, a nuclear stain. Photoreceptors are located in the outermost layer, termed Outer Nuclear Layer (ONL). These form synapses in the Outer Plexiform Layer (OPL) with interneurons, whose cell bodies reside in the Inner Nuclear Layer (INL). Bipolar and amacrine cells of the INL also form synapses in the Inner Plexiform Layer (IPL), with ganglion cells from the Ganglion Cell Layer (GCL). (B,E) Expression of HB9-GFP in V-ooDSGCs (solid arrowheads) and cone photoreceptors (open arrowheads). (C,F) Expression of Mito-CFP in Type 1a (solid arrowheads) and 1b Bipolar Cells (BCs), as well as other bipolar, amacrine, and ganglion cells. (D,G) Expression of TYW3 in several types of retinal ganglion cells (RGCs) that stratify in the middle part of the IPL. All cells are GFP positive. Scale bars (A–D) are 40 μm and scale bars (E–G) are 20 μm. Boxed regions in (B–D) are shown at higher magnification in (E–G).