Table 2.
Influence of INTs-WS2/f-INTs-WS2 at 100 µg/mL on thrombin generation parameters induced by the intrinsic pathway
| 4 µMPL | % Lagtime | % Lagtime SD | % ETP | % ETP SD | % Peak | % Peak SD |
|---|---|---|---|---|---|---|
| NPP | 100 | 9 | 100 | 9 | 100 | 11 |
| Tyrode | 81 | 1 | 110 | 4 | 112 | 6 |
| WS2 | 71 | 5 | 107 | 3 | 102 | 3 |
| WS2-COOH | 58 | 2 | 114 | 3 | 113 | 2 |
| WS2-NH2 | 48 | 3 | 130 | 5 | 150 | 19 |
| WS2-OH | 59 | 3 | 119 | 6 | 122 | 10 |
| WS2-SH | 58 | 2 | 119 | 1 | 131 | 6 |
ETP, endogenous thrombin potential; NPP, normal pool plasma
Data are expressed in percentage in comparison with control (PBS) (n = 3)