Table 2.
Psychotropic medication in 22q11DS patients per risk group.
| With psychosis n = 10 | High risk n = 4 | Low risk n = 20 | Dosage (range) | |
|---|---|---|---|---|
| Antidepressant medication | ||||
| patients treated (n = 8) | 1 | 2 | 5 | |
| total | 10% | 50% | 25% | |
| SSRI | 10% | 50% | 20% | 10–150mg |
| SARI | 10% | 25% | 5% | 50 mg |
| Antipsychotic medication | ||||
| patients treated (n = 10) | 7 | 2 | 0 | |
| 1st generation(n) | 2 | 0 | 0 | |
| total | 20% | 0% | 0% | |
| Thioxanthene | 10% | 0% | 0% | 0,5 mg |
| Pipamperone | 10% | 0% | 0% | 120 mg |
| 2nd generation (n) | 4 | 2 | 0 | |
| total | 40% | 50% | 0% | |
| Quetiapine | 0,00% | 25,00% | 0,00% | 100–180 mg |
| Quetiapine(XR) | 20,00% | 0,00% | 0,00% | 600–1000 mg |
| Paliperidone | 0,00% | 25,00% | 0,00% | 9 mg |
| Olanzapine | 10,00% | 0,00% | 0,00% | 30 mg |
| Aripiprazol | 20,00% | 0,00% | 0,00% | 10 mg |
| Other(n) | 2 | 0 | 0 | |
| total | 20% | 0% | 0% | |
| Clotiapine | 10,00% | 0,00% | 0,00% | 40 mg |
| Risperidone | 20,00% | 0,00% | 0,00% | 3–5 mg |
Psychotropic medication per subclass and risk group for psychotic symptoms. Abbreviations: SSRI = Selective serotonin reuptake inhibitors; SARI = Serotonin antagonist and reuptake inhibitors; n = number.