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. 2018 Oct 29;38(22):e00022-18. doi: 10.1128/MCB.00022-18

FIG 2.

FIG 2

Fra-2 expression in osteoblasts induces myeloid cell alterations. (A) FACS dot plots and quantification of hematopoietic stem cells (LSK, Lin− Sca1+ c-Kit+) and myeloid progenitor cells (Lin− IL-7Rα− Sca-1− c-Kit+) in bone marrow from 10-week-old Fra-2Ob-tet and littermate mice (n = 6 to 8). (B) FACS dot plots and quantification of CD11b+ cells in bone marrow from 10-week-old Fra-2Ob-tet and littermate mice (n = 8). (C) Real-time PCR analyses of the ccr2, mcp-1, GM-CSF, and G-CSF genes in bone marrow from 10-week-old Fra-2Ob-tet and littermate mice (n = 10). Data represent the mean values ± SEM. *, P < 0.05 (unpaired t test).