TABLE 1.
Absolute numbers of HSCs and myeloid cells in the bone marrow and spleens from wild-type and Fra-2Ob-tet mice
| Cell type (unit) | No. (mean ± SEM) in: |
P valuea | |
|---|---|---|---|
| Control mice (n = 4) | Fra-2Ob-tet mice (n = 6) | ||
| LSK cells (×104/whole bone) | 5.03 ± 0.66 | 3.64 ± 0.33 | 0.13 |
| Myeloid progenitors (×105/whole bone) | 1.09 ± 0.08 | 1.98 ± 0.37 | 0.07 |
| Common lymphoid progenitors (×104/whole bone) | 0.19 ± 0.02 | 0.14 ± 0.03 | 0.46 |
| Neutrophils (×106/spleen) | 1.99 ± 0.30 | 2.71 ± 0.15 | 0.04* |
| Eosinophils (×106/spleen) | 0.98 ± 0.23 | 1.35 ± 0.28 | 0.21 |
| Macrophages (×106/spleen) | 1.27 ± 0.21 | 1.58 ± 0.13 | 0.26 |
| MI macrophages (×106/spleen) | 0.94 ± 0.12 | 1.63 ± 0.19 | 0.04* |
| MII macrophages (×105/spleen) | 3.06 ± 0.76 | 2.27 ± 0.35 | 0.44 |
a
*, P < 0.05.