FIG 3.

Proliferation of CD4⁺ T cells after CD4 depletion. Expression of Ki67 on CD4⁺ T cells was measured in PBMC (A), LN (B), and RB (C) during CD4 depletion and reconstitution. (D to G) Ki67 was measured within each CD4⁺ T cell memory subset: naive (D), central memory (E), transitional memory (F), and effector memory (G). Expression of PD-1 on CD4⁺ T cells was measured in PBMC (H), LN (I), and RB (J) during CD4 depletion and reconstitution. Open symbols represent early chronic treated animals, and closed symbols represent late chronic treated animals. Each symbol represents a different animal, and the line represents the median.