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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: J Am Chem Soc. 2018 Jul 18;140(30):9392–9395. doi: 10.1021/jacs.8b05725

Table 3.

Enantioselective Iridium-Catalyzed anti-(α-Aryl)allylation of Difluoroacetaldehyde Ethyl Hemiacetal 1j to Form CHF2-Bearing β-Aryl Alcohols 5a-5l.a

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a

Yields of material isolated by silica gel chromatography. Enantioselectivities were determined by chiral stationary phase HPLC analysis. See Supporting Information for further experimental details.